A total of 214 urologists treated 2653 cases of Peyronie's Disease with para-aminobenzoacidic potassium (POTOBA). The treatment was successful in 57.3% and unsuccessful in 42.7% of the cases; 246 patients (9.3%) were 'cured. Particular prescriptions intended to increase gastric tolerance and thereby guarantee long-term use of the medication are pointed to as a prerequisite to successful therapy. Practical advice is presented on how to interest patients in carrying out long-term treatment themselves.